MéCour Thermal Blocks can be utilized in a wide range of chemical, immunological and biological assays. The adaptable design is equally suited for applications both on the laboratory benchtop or for integration onto an automated/robotic/HTS platform. Assays requiring precise temperature maintenance, including thermal cycling, can be run using a MéCour Block without the need to manipulate assay plates, tubes or vessels. Sensitive reagents can be maintained at specific temperatures and reservoirs are easily accessible right at the workstation. MéCour technology effectively removes temperature as a concern in assay precision by improving assay optimization/qualification/validation efforts.

Below is a listing of assays that have been successively implemented utilizing the MéCour technology:

Microplate Assays:

Cell-based assays:
Drug Screening Applications
Kinase Screens
MAPKAP Screens
In Vitro Cytotoxicity
Apoptosis/Necrosis
ADME-Tox

Biological assays:
Chromogenic Endopoint LAL Assay
ELISA
Cell based screening
Microsomal Screening

Enzymatic applications:
Fluorescence/Quencher release assays
DNA/RNA restriction enzyme cleavage
Digestion procedures

Genomics applications:
DNA purification and clean up
DNA/RNA amplification

Microbiological
Sub-culture procedures
Culture incubation
Culture isolation
Media preincubation
Growth promotion

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Tube-based Assays:

DNA Plasmid Preps
Magnetic bead assays
Precipitation reactions
Combinatorial/general wet chemistry

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Vessel Applications:


BioProcessor scale up studies for recombinant biopharmaceuticals
Homogenization of tissue/vegetative samples
Ammonium sulfate (protein) precipitation procedures
Melting of oils/lipids

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